Blood tests could detect breast cancer years before

The Telegraph  reported that scientists funded by the Cancer Research Campaign have found that a simple blood test could help identify women most at risk from breast cancer.  

Researchers discovered a strong association between risk of the disease and a molecular change in a particular white blood cell gene. They also looked for a chemical effect called methylation, which is known to act as a “gene switch”.  Women showing the highest methylation levels affecting the ATM gene were twice as likely to develop breast cancer compared with those with the lowest levels.

The test could help doctors to identify women at high risk of the disease years in advance allowing them to take preventive medicines and switch to healthier lifestyles.

Baroness Delyth Morgan, chief executive of Breast Cancer Campaign, said: “this research is so exciting because it suggests that there is every possibility the risk of developing breast cancer could be decided many decades in advance…..By piecing together how this happens, we can look at ways of preventing the disease and detecting it earlier to give people the best possible chance of survival.”

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A new prostrate cancer treatment could remove the disease with fewer side effects

The Guardian reported that a study has revealed that a new treatment for prostate cancer could remove the disease from nine in ten men without debilitating side effects, leading to new hope for tens of thousands of men.

Researchers at UCL have conducted a small study of focal therapy which shows a dramatic fall in rates of incontinence and other problems after treatment. The study was the first to use an experimental treatment known as HIFU (high-intensity focused ultrasound) to treat areas of cancer that are only a few millimetres in size, a technique known as focal therapy.

Dr Hashim Ahmed, who led the study at University College London Hospitals NHS Foundation Trust and UCL, said: “Our results are very encouraging. We’re optimistic that men diagnosed with prostate cancer may soon be able to undergo a day case surgical procedure, which can be safely repeated once or twice, to treat their condition with very few side-effects. That could mean a significant improvement in their quality of life.

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Quintiles Named Best CRO In Vaccine Excellence Awards 2012

Pharmiweb reported that Quintiles has been named best Clinical Research Organization (CRO) in the Vaccine Industry Excellence (ViE) Awards 2012.

The awards recognize and celebrate the leaders, innovators and pioneers in the vaccines industry.  The awards were  presented at the World Vaccine Congress in Washington, D.C.

Customers voted for their preferred CRO prior to the World Vaccine Congress and a judging panel then made its selection based on a set criteria.

Dr. Ellen Vigdorth, VP Allergy, Respiratory, Infectious Diseases and Vaccines. “This is a great honor to be recognized as the Best CRO at the World Vaccine Congress…It is a huge achievement and underscores our commitment to the development of quality vaccines and anti-infective products.”

Are you looking for a new job in the clinical research industry? Click here to see our most recent clinical research jobs!

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GSK Breast Cancer Trial Scaled Back

Inpharm.com has reported that GlaxoSmithKline is to scale back a phase III clinical trial looking into potential breast cancer treatments.

The trial, which has been running since 2007, is evaluating the effectiveness of the breast cancer drug Tyverb in four different combinations, following surgery. The patients in the trial receive either Tyverb, Roche’s established drug Herceptin, Herceptin followed by Tyverb or both drugs.

An interim report has indicated that the patients only receiving Tyverb are not demonstrating any improvement compared to Herceptin, so that arm of the trial has been discontinued. Those who are halting their treatment are to discuss other options with trial physicians. 8,400 patients are taking part in the study, and the remaining three trials are to continue as normal.

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Lead CRA looking for new positions in the London area

Susan is currently working with an excellent candidate who is looking for either contract or permanent work in the London area. Watch this video to find out more!

[youtube]http://www.youtube.com/watch?v=9Lvyo9_sDQE[/youtube]

This Lead CRA has recently come to the end of his contract, and is ideally seeking either Associate Clinical Project Management roles, or Associate Clinical Study Management roles. He has vast experience in oncology, cardiovascular and CNS.

To find out more about this candidate, please contact Susan on 01438 743 047 or email smurray@ckclinical.co.uk.

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Our Latest Clinical Jobs…Apply Now!

Here are a selection of our latest Clinical roles. For more information, please contact Jim Gleeson at CK Clinical o 01438 743 047 or email jgleeson@ckclinical.co.uk.

 

Senior Clinical Research Associate, Oncology

  • Permanent
  • Competitive salary

 

Senior Clinical Research Associate position with a successful, international Clinical Research Organisation. You will monitor Oncology studies being carried out at sites around the UK to ensure all activities are compliant with the protocol, ICH-GCP requirements and company procedures and quality standards. The position will be office based in the home counties.

Clinical Compliance Officer

  • 3 month interim project
  • Good Daily rates
  • Manchester based with European Travel

 

A exciting and rate interim opportunity for a Clinical Compliance Officer to join a global pharmaceutical company has arisen. As a Clinical Compliance Officer you will be helping Local and Regional Compliance Officers to implement a new Global Compliance Framework. You will also be key in providing a project management type structure to deliver the new Compliance Monitoring processes quickly and robustly.

GCP Auditor

A superb opportunity for an experienced GCP Auditor to work with a leading global pharmaceutical company on a long term contract, twelve months initially, ongoing thereafter.  Although you will report to their UK Head Office the role can actually befield-based anywhere in the UK. You will have responsibility for audit activities (Investigator Sites and Vendors) throughout Europe to ensure robust audit plans and constant inspection preparedness. Duties will also include risk identification and associated audit programme development, delivery of audit reports, ensuring preventative actions are carried out and supporting the group’s training and compliance functions.

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Government Plan to Speed up Clinical Research

As reported by Reuters, the government will be looking to implement systems to help speed up clinical research in order to reduce red tape, thus making healthcare innovations more quickly available to patients.

The Academy of Medical Sciences (AMS) has put forward plans to create a new Health Research Agency which would act as a single portal for approvals needed in clinical research.

Michael Rawlins of the AMS stated, “The regulatory and governance environments for doing health research in the UK have been utterly stifling. Over the last 10 years there have been more and more regulatory and governance measures put in place … and the cumulative effect has been devastating. We cannot go on like this.”

The plans have been welcomed by a number of pharmaceutical industry groups as well as Health Minister, Andrew Lansley.

Are you looking for a new position in the UK pharmaceutical industry? Click here to search our current pharmaceutical and clinical research jobs online now.

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CK Clinical to Speak at the Recruiter Annual Forum 2010

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CK Clinical, a leading recruitment agency handling jobs in clinical research and drug development, has been invited to join the panel of speakers at the Recruiter Annual Forum 2010 which will be taking place on 23rd March 2010 in central London. The Recruiters Annual Forum attracts a senior level audience of recruitment professionals from all industry sectors including those who specialise in recruitment for the pharmaceutical industry.

As an active user of social media to attract and support jobseekers in the pharmaceutical industry, CK Clinical will be speaking about the ways we have built, differentiated and managed our brand on the internet. Further topics will include:

  • Our move away from traditional methods towards a more transparent, web-based recruitment.
  • The social media sites at which should recruitment agencies invest their time: LinkedIn, Facebook, Twitter, Xing and Ning.
  • How does CK Clinical achieve brand differentiation online?
  • Managing user generated content and protecting our brand’s reputation.
  • How will companies be using social media in 12 months time?

To keep up to date with all the key issues that will be addressed at the Recruiter Annual Conference you can join their Linkedin Group here.

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