£50million investment fund created to bridge cancer drug development gap

Pharmatimes have reported that a £50 million pound fund has been created by Cancer Research Technology (which is Cancer Research’s commercial section) and the European Investment Fund. This funding is to bridge the gap in the UK between cancer drug discovery and early development.

CRT and the EIF will make equal contributions to the CRT Pioneer Fund, which has launched with a first contribution of £25 million. This may be doubled by the founders to reach the total £50 million, they note.

The aim is to address the so-called “valley of death” funding crisis facing early-stage drug development, which is caused by investors not investing in high-risk projects like drug research in the wake of the financial crisis.

Dr Harpal Kumar, chief executive of Cancer Research UK said ”This vital investment will nurture world-class innovation in drug development to bring potential new treatments to patients as quickly as possible”

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Clinical Imaging Associate Job in Uxbridge

Russell Oakley at CK Clinical is currently recruiting for a Clinical Imaging Associate to join a global drug research and development company based in Uxbridge.


As Clinical Imaging Associate you will:

  • Conduct set-up of clinical trials within the internal imaging system under limited supervision
  • Proactively participates in a partnership with the matrix partners
  • Ensure trials are validated before going live
  • Understand financial drivers and their role in decision making
  • Ensures that the conduct of imaging work meets GCP requirements
  • Conduct image review against basic parameters (QC)
  • Raise queries using eDC system or alternative
  • Interact with wider stakeholders, e.g. CROs/vendors (Image Transfer CROs) and monitors.
  • Proactively track timelines and identify issues in order to propose strategies to implement

contingencies and risk planning to meet overall study/program goals.

  • Input into study plans and process documents.
  • Forecast and monitor data volumes within studies and/or across programs
  • Conduct end-of-study learning debriefs for study team
  • Provide input into process improvement initiatives.
  • Identify and disseminate best practices and standardization
  • Assure the quality of the deliverables.
  • Facilitate effective communication and teamwork


To be considered for this Clinical Imaging Associate position, you will have:

  • A Bachelors degree or equivalent, major course of study in Science or Health-related preferred
  • 2 years experience in clinical research
  • Strong computer literacy
  • Awareness of GCP and its application to clinical trials
  • Interpersonal skills associated with working in a matrix team
  • Solid understanding of clinical practices.  Understands impact of changes and is able to apply

changes to study design and potentially program level decisions.

How to apply:

Click here to apply online now.

For more information regarding this Clinical Imaging Associate position, please contact Russell Oakley at CK Clinical on +44 (0) 114 283 9956 or email roakley@ckscience.co.uk. Please quote reference CL24004 in all correspondence.

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Pfizer Forges Partnerships in Cambridge

Business Weekly reported that Pfizers R&D model at the Cambridge UK Life Sciences Cluster is already a success. Regenerative medicine is based at the Granta Park Science Park in Cambridge.

Pfizer is currently forging ahead making partnerships with small UK Biotech companies that are boosting the innovation pipeline and promise to accelerate the pace of new medicine discovery.

Pfizer – Neusentis (Pfizer’s new research unit) held a networking event last week at Granta Park during Cambridge Awards Week called Partnering with Neusentis, an entrepreneurial Pfizer research unit at the forefront of the new pharma R&D model. Influential people from the life sciences and VC communities attended and were said to be pleased with the initiative.

Dr Ruth McKernan who is a senior vice president at Pfizer and chief scientific officer at Neusentis was pleased with the reaction to the initiative. She said told Business Weekly that “the Cambridge hotspot is proving to be fertile territory for the new and highly focused R&D model that Pfizer is pioneering” She also said that half a dozen potential collaborations had been identified in the last week alone in Cambridge and that small businesses in the sector were often a major source of innovation in their own right.

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Clinical Manager Job in Home Counties

Jim Gleeson at CK Clinical is currently recruiting for a Clinical Manager to join an international pharmaceutical company at their site based in the Home Counties.

As Clinical Manager, you will have responsibility for all aspects of study management for assigned global studies from the concept and planning stage through to close-out. This will include resource allocation, documentation development, vendor selection and management, supplies management and CSR review.

To be considered for this Clinical Manager position, you will have the following skills and experience:
– Clinical project management experience on an EU or global basis, from start-up to close-out
– Urology trial experience would be advantageous
– The ideal candidate will also have had experience of trial monitoring
– Thorough understanding of ICH-GCP requirements
– Ability to travel up to 25%

How to apply:

Click here to apply online now.

For more information regarding this Clinical Manager position, please contact Jim Gleeson at CK Clinical on 01438 743 047 or email jgleeson@ckclinical.co.uk. Please quote reference CL23976 in all correspondence.

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Boehringer Ingelheim expands its biopharmaceutical development and manufacturing capabilities

Ingelheim Boehringer New’s Centre released a press statement announcing that it has expanded its biopharmaceutical development and manufacturing capabilities at its cell culture and microbial sites in Biberach, Germany and in Vienna, Austria

The press statement said that 17 million Euros has been invested which has meant  the expansion of Boehringer Ingelheim’s current GMP (good manufacturing practice) cell banking, process science, cell line development and quality laboratories, all equipped with the latest technologies.   These expansions will enhance state-of-the art cell line development with the proprietary BI-HEX® high expression system and microbial strain as well as process development services for the contract manufacturing business.

The expansion has been taylor-suited to fully meet our customer demands in cell culture and microbial process science, especially for our rapidly expanding pre-clinical project portfolio with biotech companies”, commented Dr. Dorothee Ambrosius, Senior Vice President Biopharmaceuticals Global Process Science at Boehringer Ingelheim.

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Eli Lilly invests Cork Ireland site making 200 jobs

Eli Lilly in Ireland released a statement reporting that the Minister for Jobs, Enterprise and Innovation Richard Bruton TD announced that Eli Lilly and Company, a global leader biopharmaceuticals, is to invest €330 million in a brand-new facility at its Kinsale campus.

The investment will lead to the creation of 200 new jobs at the facility, as well as a further 300 construction jobs which will be created as part of the building works. This will bring Eli Lilly’s total employment in Ireland up to almost 1,000.

The investment will expand the Kinsale site’s existing biopharmaceutical mission with the establishment of an additional world-class commercialisation and manufacturing facility.

The planned 240,000-square-foot biopharmaceutical commercialisation and manufacturing facility will further enhance the company’s ability to bring treatments for illnesses such as cancer and diabetes to patients worldwide

“This investment is an endorsement of the Lilly Kinsale site’s success in developing a biopharmaceutical business in recent years and demonstrates our ability to rise to that challenge. This is in no small part due to the site’s excellent performance record, the talent of the workforce, and the support from IDA Ireland,” said Ed Canary, general manager of the Kinsale site.

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Scottish Government and PPD to Advance Research

The Scottish government and Pharmaceutical Product Development, LLC (PPD) announced a unique alliance designed to increase the amount of clinical research conducted in Scotland, accelerate the development of new medical therapies and enhance health care treatment options for the people of Scotland.

The US-based contract research organisation (CRO) has a longstanding relationship with the Scottish government and employs more than 300 clinical research professionals at its facility in Bellshill, Lanarkshire.

PPD will work closely with the major health boards across Scotland to further reduce study start-up times, streamline regulatory approval processes, increase the number of patients recruited for clinical trials and ensure the availability of resources and training to increase the number of physicians and support staff conducting research.

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GW Pharma seeks FDA approval for cannabis drug

As reported by the Daily Mail, the UK pharmaceutical company, GW Pharma is currently seeking approval from the US Food and Drug Administration (FDA) for their cannabis-based drug.

The drug, which is a mouth spray called Sativex is made from raw marijuana and is used to treat cancer pain. The drug is currently in advanced clinical trials and GW Pharma hope to receive approval by the end of the year.

Sativex is the first of it’s kind which is derived from raw marijuana – previous drugs have  used the synthetic alternatives. It contains two of marijuana’s best known components – delta 9 and cannabidiol. It ahs already been approved in New Zealand, Canada and eight European countries for the treatment of muscle spasms associated with multiple sclerosis.

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Director of Clinical Development Job – London

Ben Traies at CK Clinical is currently recruiting for a Director of Clinical Development to join a successful and expanding pharma company based in Greater London.

The role:

As Director of Clinical Development you will have responsibility for the oversight and management of clinical development programs for a portfolio of cardiovascular products from early development through to the market.

You will be the point of contact for interactions with regulatory -agency clinical reviewing divisions on clinical matters, oversee management and performance of CROs and ensure high quality products for the business.

Responsibilities also include:

  • Prepare Clinical Development Plans
  • Manage budgets
  • Specify go / no-go criteria
  • Provide medically based advice to non-clinical and commercial colleagues
  • Provide input to the assessment of products in consideration for in-licensing


The ideal candidate:

Ben is looking for candidates with the following skills, experience and qualifications:

  • Medical degree
  • Proven pharmaceutical clinical development experience, preferably with cardiovascular products
  • Excellent communication and project management skills
  • Expertise in clinical trial design, operations and interpretation of scientific data
  • Willingness to travel internationally as required


How to apply:

For more information or to apply for this Director of Clinical Development position, please contact Ben Traies on 01438 870021 or email btraies@ckclinical.co.uk. Please quote reference CL23028 in all correspondence.

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ABPI code often neglected

As reported by The Pharma Times, neglect of the Association of British Pharmaceutical Industry (ABPI) code is growing more and more common.

There have been a number of high profile campaigns which have been found to be in violation of the ABPI Code. Such campaigns have been found by the Prescription Medicines Code of Practice Authority (PMCPA) to either:

  • Encourage patients to request that their healthcare professional prescribe them a certain prescription-only medicine (POM)
  • Advertise POM’s to the public
  • Promote an unlicensed indication

The ABPI Code states that communications with patients must be:

  • Non promotional
  • POM should NOT be advertised to the public
  • Factual and balanced
  • Should not mislead in terms of safety
  • Communicated in such a way that members of the public are NOT encouraged to ask their health care professionals to prescribe them a certain medicine.

However, many in the industry disagree with these findings and highlight the need for pharmaceutical companies to be creative in their communications to patients. Some believe this is growing in importance due to the rise in popularity of mediums such as Facebook, blogging and apps among patients.

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