LC-MS Scientist

  • Salary: Competitive
  • REF Number: v-51658
  • Consultant: Georgia Barnes
  • Contact: 01246 457722
  • Date Published: 25.04.2024
  • Industry: Biotech
  • Location: Macclesfield, Cheshire, England
  • Functional Expertise: Research & Development

CK Group are recruiting for a lab-based LC-MS Scientist to join a precision medicine company based near Manchester.

Company:

Our client is developing next-generation diagnostic tests to help clinicians prescribe the right drug, for the right patient, at the right time. They are developing LC-MS proteomic biomarker discovery platforms and clinical assays to predict drug response in a clinical setting.

The Role:

  • Support the development of biomarker discovery platforms and resulting clinical assays.
  • Be involved in a variety of projects that aim to expand the portfolio of proteomic assays
  • Sits within the LC-MS/MS technical operations team and involves operation of LC-MS/MS systems and method development

Your Background:

  • Ph.D. in proteomics or protein biochemistry applied to the investigation of mammalian cell biology
  • Expertise in LC-MS/MS proteomics - hands-on experience running/operating high-end LC-MS/MS systems (including hands-on experience calibrating the MS systems, basic maintenance of LC-MS/MS, renewing buffers, running QCs, interpreting data, and reporting QC outputs).
  • Experienced in preparing samples using proteomic workflows for LC-MS/MS analysis.
  • Experience working with multiple sample types (e.g. cell lines, blood, solid tissue).
  • Knowledge and understanding of fundamental principles of biochemical and molecular biological systems. 

Desirable:

  • Experience analysing large sample sets, across multiple batches.
  • Experience using software for the identification, characterisation and quantification of peptides and proteins from LC-MS/MS raw data.
  • Expertise in the utilisation of LC-MS/MS proteomic technologies for the identification and validation of clinical biomarkers.
  • Experience in automation of sample preparation workflows using liquid handlers.
  • Experience building targeted (e.g., PRM/SRM) or untargeted (e.g., DDA/DIA) methods for proteomics. 

Apply:

It is essential that applicants hold entitlement to work in the UK. Please quote job reference T56527 in all correspondence.

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